sqlite

A 2006 Google TechTalk in which SQLite's author Richard Hipp introduces the embeddable, zero-configuration C database library. He covers its history, strengths and weaknesses, and where it beats client/server databases.

Cuong Do of YouTube describes how a handful of engineers scaled the site, covering hardware, software and database scalability challenges during its rapid growth. The talk was given at the 2007 Seattle Conference on Scalability.