david sinclair

Harvard geneticist David Sinclair discusses his book Lifespan at Google. He covers the biology of aging, lifestyle interventions and possible future ways to slow or reverse it.

David Graeber's Talks at Google presentation on his book Debt: The First 5,000 Years, covering the history of debt, the myth of barter and the Jubilee tradition.

David Foster Wallace's 2005 commencement speech at Kenyon College, about the default settings of the mind, choosing what to pay attention to, and what we end up worshipping.

David MacKay's TEDxWarwick talk uses basic arithmetic to show how much land and energy renewables would need to power a country like the UK. It explains the limits of sustainable options and why they should still be pursued.

David MacKay, scientific advisor to the UK energy department, gives a Harvard talk on sustainable energy at macro and micro scale, drawn from his book Sustainable Energy Without the Hot Air. It stresses the land area renewables require.

A short video of David Foster Wallace's 'This Is Water' commencement speech about awareness and choosing how to think. It argues that the most obvious realities are the hardest to see, using the fish-in-water parable.

David Nolen explains how ClojureScript is used at Vouch.io to build mobile and web software with a single language and REPL-driven workflow. The talk includes a live coding demo of React Native development.

Physicist David Deutsch's TED talk on why science took off, arguing that good explanations are those that are hard to vary. It contrasts scientific explanation with myth.

An excerpt from an RSA event in which physicist David Deutsch makes the case for optimism as a driver of progress in the 21st century. It is a short highlight of a longer discussion.

A 2015 talk by David Deutsch with slides and audio about constructor theory and how physics, in particular the many-worlds interpretation, can be framed without probability.

David Kriesel's FrOSCon talk on how Xerox scancopiers, due to JBIG2 compression, silently replaced digits in scanned documents. He walks through how he discovered the bug and why it is so dangerous.

David Patterson's talk on the history of computer architecture, from RISC and superscalar designs to the end of Dennard scaling and Moore's Law. It argues that domain-specific architectures and open instruction sets open a new golden age.

Retired submarine captain David Marquet explains, with drawings, how he turned the USS Santa Fe around by treating his crew as leaders rather than followers. It summarizes the ideas of his book Turn the Ship Around.

David Deutsch's TED talk arguing that humanity's survival depends on solving problems through knowledge growth. He frames people as improbable "chemical scum" capable of understanding distant quasars.

David Beazley's PyCon 2010 talk explains how the Python Global Interpreter Lock works and shows experiments where multithreaded code runs slower, even on more cores, due to lock contention and context-switching overhead.

David Heinemeier Hansson's talk at Startup School 2008 on building a profitable startup. He argues for bootstrapping and small, well-run companies instead of chasing investment and exits.

David Kriesel's 31C3 talk, in German, on the discovery that Xerox scanner-copiers silently replace digits and letters in scanned documents. He explains how the bug stayed unnoticed in the wild for years.

Actress Claudia Christian tells how she overcame alcoholism using the Sinclair Method, which uses naltrexone to gradually reduce cravings. She discusses fresh perspectives on treating alcohol use disorder.

David Crane, designer of Pitfall for the Atari 2600, gives a GDC 2011 postmortem on the game's design challenges. He covers how he fit a large world into the console's tiny memory. The session ends with Q&A.

David Heinemeier Hansson's RailsConf 2014 keynote argues that programming is closer to writing than to science, with clear code produced by iterating through drafts. It prioritizes clarity and craft over technical superiority.

David Heinemeier Hansson's opening keynote at RailsConf 2019 argues against the expectation of payment for open source work, drawing on his experience releasing Rails. It also includes lighter asides about the industry.

David Nolen presents Om Next, the redesign of the ClojureScript Om library, drawing on Relay, Netflix's JSONGraph and Datomic. He covers the tradeoffs in handling the client-server boundary over immutable data.

David Epstein argues in this TED talk that improving athletic records owe much to technology, training and the selection of specialized body types, not just humans getting inherently better. He gives counter-intuitive examples across sports.

David Heinemeier Hansson, creator of Ruby on Rails and partner at 37signals, argues that planning is guessing and startups should focus on today. He says constraints are an advantage and that startups can bootstrap profitably in sizable markets.

David Kriesel's 36C3 talk, in German, analyzes a year of scraped data on every stop of every long-distance train in Germany. It shows how Deutsche Bahn delay statistics hide cancellations and delays.

David Weston's BlueHat IL 2023 talk traces the evolution of Windows security and previews Windows 11 and hardware advances. It ends with upcoming changes such as Rust in the kernel and fonts, signed binaries and adminless Windows.

David Christiansen gives a Strange Loop 2018 introduction to dependent types, where one language serves for both compile-time and run-time code and programs unite with proofs. It draws on his book The Little Typer.

David Mazieres presents the Stellar Consensus Protocol at Google, introducing federated Byzantine agreement. The model lets participants choose whom to trust rather than assuming fixed membership.

David Nolen reviews the first five years of ClojureScript, documenting its landmarks and looking ahead to the next five. It is a history-and-roadmap talk from the Clojure community.

David MacKay's 2007 Google Tech Talk presents Dasher, a text-entry system driven by continuous gestures and a language model, reaching about 35 words per minute with one finger and 25 hands-free. It explains the information-theory reasoning behind the design.

David Ungar of IBM Research reflects at Stanford on the Self language project and argues the real legacy of ideas is the people. He covers its history, philosophy, successes and failures.

DHH's opening keynote at Rails World 2024 in Toronto, where Rails 8 beta shipped. It covers built-in authentication, Propshaft, Solid Cache, Solid Queue, Solid Cable, Kamal 2 and Thruster, pitching the One Person Framework that needs no PaaS.

David Rock gives a Google Tech Talk based on his book Your Brain at Work, using neuroscience to explain why focus and productivity are hard at the office. He gives strategies for managing mental energy and distraction.

David Beazley's PyCon India closing keynote, in which he live-codes a stack machine and grows it into an interpreter that runs WebAssembly, then uses it to play a Rust-written game. It requires no prior WebAssembly knowledge.

David Heinemeier Hansson explains what he learned about indoor air quality after his new house made his family sick. He covers CO2, VOCs, off-gassing, HVAC and ventilation, and cognitive effects, presented at a Basecamp meetup.

David Beazley's PyData Global 2021 keynote, an oral history of early scientific Python. He tells how Python ended up running on a Connection Machine supercomputer at Los Alamos.

David Brevik's GDC 2016 postmortem of Diablo covers how it went from a turn-based claymation DOS concept to a real-time action RPG, plus the story of Blizzard North and development anecdotes.

Bungie's David Aldridge explains the networking programming behind Halo: Reach in a 2011 GDC session. It covers how gameplay stays in sync online, including forecasting and state reconciliation.

David Guillot describes how his team replaced a two-year-old React UI of their SaaS product with Django templates and htmx in a couple of months. The talk gives concrete indicators on code size, performance and team impact.

David Kriesel's 36C3 talk, in an English translation, analyzes a year of scraped Deutsche Bahn data covering every stop of every long-distance train in Germany. It explores delays and how punctuality is actually measured.