diy biotech

Ben Krasnow of Applied Science builds and operates a simple mass spectrometer, using it to measure potassium isotopes in a salt substitute. He explains the design choices and the theory behind it.

This Old House's Ross Trethewey explains MERV filter ratings and how air filtration works, then shows how to build a localized DIY air filter, including a box fan with multiple filters.

Tech Ingredients shows how to build cheap, high-performance flat-panel speakers using audio exciters on sheet materials such as foam-core board. It explains how distributed-mode speakers work and walks through experiments to find good designs.

Ben Krasnow shows the first image from his home-built scanning electron microscope, after months of work, and walks through how the parts operate together.

A hobbyist builds a prototype full-frame CCD camera from scratch, with open-source design files and a custom PCB. The video shows the first, still rough prototype.

Ben Krasnow of Applied Science builds a DIY microbalance from an analog panel meter with an optical servo loop. It reaches about 5 micrograms of precision and is used to weigh a single eyelash at around 35 micrograms.

The Thought Emporium shows how they engineered a yeast strain to produce real spider silk, after more than two years of lab work and many failures. The video explains the genetic engineering process behind it.

Essential Craftsman follows up on his earlier video about a DIY approach to sleep apnea. It centers on forcing nose breathing during sleep with mouth taping and nasal strips, and says to seek medical guidance.

The Thought Emporium's host describes making and taking a DIY gene therapy to treat his own lactose intolerance. It uses an AAV virus to deliver DNA coding for the lactose-digesting enzyme, made with biohacker Gabriel Licina's help.

The Thought Emporium grows living rat neurons on an electrode array and tries to train them to play Doom. It is part of a series on biological computing.

A DIY demonstration of a fan-and-screen mosquito trap that uses carbonated water as a CO2 attractant. The creator reports catching about 8,000 mosquitoes in two nights.

The Thought Emporium's update on the home-brewed gene therapy he took to cure his lactose intolerance. It reports how the effect held up over two years and what future versions might look like.

The Thought Emporium builds a homemade multi-electrode array, grows human neurons on it and attempts to take readings. It is the first part of a series aimed at connecting living neurons to a computer.

The Thought Emporium shows how easily bacteria can be genetically modified to produce fluorescent proteins and even bioluminesce, with techniques doable at home. It links to companion videos on incubators, DNA extraction and gels.

Tech Ingredients shows how to build flat panel speakers from exciters and foam board, with construction guidelines, measured SPL comparisons and a complete system playing music.

Cody's Lab builds a prototype algae growing panel as an experiment before making more. The channel also shows growing algae for consumption.

DIY Perks builds a realistic artificial sun for dark winters, using a powerful water-cooled LED, a satellite dish reflector for near-parallel rays, and a scattering layer to mimic the blue sky. The video explains the optics behind why most lamps do not look like sunlight and shows the build and its results.

DIY Perks shows how to turn old or smashed TVs and monitors into realistic artificial window lights, using the backlight and Fresnel lens to simulate distant daylight.

DIY Perks builds a webcam mod using a two-way mirror in a box so the camera sits behind the screen image. This allows real eye contact on video calls.

DIY Perks shows how to modify devices that use older USB connectors so they charge and connect over USB Type-C. He solders in a USB-C connector board and works through cases such as dongle-dependent gadgets and a mouse receiver.

The first installment of a hobbyist's video diary documenting his build of a giant walking spider-like vehicle. The footage is casual and self-shot, following the early stages of the project.

A woodworker shows how his table saw accident happened, why it happened and how to avoid a similar one. He describes severe hand lacerations from a blade contact.

Tech Ingredients shows how to make a homemade radiative cooling paint, with a custom liquid panel that cools below ambient temperature outdoors. The video covers the materials and how to apply the paint.

NightHawkInLight shows how to make radiative sky cooling paint from grocery and hardware store materials, including a novel calcium carbonate microsphere synthesis. The paint can cool a surface below ambient air temperature in direct sunlight without electricity.

NightHawkInLight shows how to make ultra-white radiative paint that cools surfaces below ambient temperature without electricity. He walks through the research papers and the household-materials process.

A University of Michigan Medicine demonstration of building a cheap DIY air purifier from a box fan and a HEPA or high-MERV filter using hardware-store parts. It explains why this helps against dust, smoke and viruses and ties it to local air quality readings.

Zack Freedman gives advice on why makers fail to finish projects, including scrapping bad ideas, showing work publicly and writing a plan that keeps projects fun. It is aimed at hardware DIY but generalizes.

Jared Mauch tells how he got fed up with poor internet options in rural Michigan and built his own fiber network to his town. The talk was given at NLNOG Live in September 2020.

Jeri Ellsworth demonstrates a PMOS transistor she fabricated herself in a home chip lab. She shows some of its electrical characteristics.

A two-minute demo of SmartKnob View, an open-source input knob built from a brushless gimbal motor, magnetic encoder and round LCD. Closed-loop torque control gives software-defined detents and end stops.

Tech Ingredients builds a larger solar-powered desiccant air conditioner that uses a calcium chloride liquid desiccant with evaporative cooling to cool their lab. The video includes the engineering calculations.

Peter Sripol shows his homemade Part 103 electric airplane flying, built from hobby brushless motors and batteries. The video covers the first flight out of ground effect.

Tech Ingredients builds a pair of large Voigt speakers and explains ported, transmission line and horn designs. It tests them in an anechoic chamber and uses constrained layer damping for the enclosure.

Short BBC Earth clip from Life of Mammals in which David Attenborough shows orangutans imitating human behaviors like washing clothes with soap and using tools.

A short project video in which Greg Raiz turns a 32-inch eInk display into a wireless digital newspaper showing daily front pages. It runs for months on battery, and the code is published on GitHub.

Michael Levin's NeurIPS 2018 talk on bioelectric computation outside the nervous system, showing how cell electrical networks shape development and regeneration. It covers morphological information processing in living tissue.

A two-hour Joe Rogan Experience conversation with mycologist Paul Stamets about fungi, mycelium, bioremediation and medicinal mushrooms. It touches on Lion's Mane, psilocybin and the many uses of fungi.

John Sotos, a physician and former Intel chief medical officer, argues at DEF CON 25 that genetic diseases are exploitable vulnerabilities in the genome. He warns that CRISPR and related tools will make malicious genome hacks and targeted bioweapons feasible.

A compilation of molecular animations of DNA replication and gene transcription by Drew Berry and Etsuko Uno at WEHI, made with no narration. It shows molecular machinery at work inside cells.

A short animation from the DNA Learning Center showing how mRNA carries a gene's message to the ribosome, where tRNA and codons are used to assemble amino acids into a protein.