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CGP Grey explains why European diseases devastated the Americas while few deadly diseases traveled the other way. He ties it to livestock domestication, dense cities, and the ideas of Guns, Germs and Steel.

Vsauce explores how human reasoning works, drawing on the social theory of reason and the extended mind thesis, made in partnership with Bill Gates around climate change.

A Medlife Crisis video by cardiologist Rohin Francis on overdiagnosis and over-screening. It explains how detecting more disease does not necessarily mean saving more lives, and covers harms such as unnecessary treatment.

Kurzgesagt's animated explainer on the human immune system, describing the body as an ecosystem and how immune defenses cope with the variety of invaders. It promotes their book Immune.

Adam Savage shows a set of Mitutoyo ceramic gauge blocks and uses them to explain metrology, the science of measurement. He argues that accuracy and precision work differently than most people assume, which changes how you think about every measuring tool.

An animated xtranormal explainer on quantitative easing, what the Federal Reserve was doing and how things got there. It was made by Omid Malekan.

A Kurzgesagt animation on using gene drives to modify mosquitoes against malaria, and whether we should. It explains the mechanism and the ethical trade-offs.

A two-minute clip of Andreas Antonopoulos explaining why a 51% attack on Bitcoin would not destroy it and what such an attack would cost. It is a succinct take on mining security.

Rational Animations explains Robin Hanson's grabby aliens model, which argues that humanity looks suspiciously early in cosmic history. Expanding civilizations set a deadline that explains our timing and bears on the Fermi paradox.

Veritasium explains why the one-way speed of light has never been measured, only the round-trip speed, since measuring it requires synchronized clocks that assume the answer. It explores the implications for relativity.

Robert Miles goes through ten common reasons people give for dismissing AI safety, adapted from Stuart Russell's list, and answers each one. It is aimed at skeptics and newcomers.

A short How to ADHD explainer, featuring Brendan Mahan, on why simple tasks can feel impossible for people with ADHD. It introduces the 'wall of awful', a pile of past failures, shame and anxiety that builds up in front of a task and blocks starting it.

Johnny Harris investigates why McDonald's ice cream machines are so often broken, covering the Taylor machines, the repair restrictions on franchisees and the Kytch workaround device.

Joseph Everett compares the food environment of the US, with roughly 30% obesity, to Japan's, around 3.5%. He argues that what is available and normal to eat explains much of the gap.

CGP Grey explains why horses could be ridden and why other animals like zebras and bears were never domesticated for war or riding. It is a follow-up on the topic of animal domestication.

Vox explainer arguing the two Boeing 737 Max crashes were not just a software bug but the result of a company's drive to beat its rival, with a flawed MCAS design.

David Spiegelhalter, Professor of the Public Understanding of Risk, uses statistics to weigh everyday risks such as bacon sandwiches and cycling. The six-minute piece introduces micromorts as a way to compare the risk of dying.

Minutephysics compares how efficiently different processes convert mass to energy per E=mc^2, from fire and fission to fusion, antimatter and black holes, which can convert a large fraction of mass to energy.

A short animated explainer that stages a $100 footrace in which contestants start at different distances from the line, depending on the advantages or disadvantages they inherited. It uses the race as a metaphor for how unequal starting points shape outcomes, citing US census income and poverty figures.

A short video telling how Xerox PARC invented the graphical user interface and how Steve Jobs's 1979 visit influenced Apple's Lisa.

A Vox explainer on how the wildlife trade and wet markets are linked to coronavirus and why new diseases keep emerging in China. It stresses that most people in China do not eat wildlife.

Ivor Cummins gives an 82-minute presentation on the history and science of vitamin D and human health. He draws on expert interviews to argue that sun exposure and vitamin D status are linked to many chronic diseases.

A short clip from Carl Sagan's Cosmos in which he explains how Eratosthenes measured the circumference of the Earth using shadows in two Egyptian cities. It is a clear, visual account of an ancient scientific feat.

Matt Parker of Stand-up Maths asks whether a country's reported land area accounts for hills and mountains, working through how surface area depends on the resolution of elevation data. It follows up on a question from a viewer and work by researchers who measured it.

Historia Civilis traces the history of work and time discipline, comparing modern working hours with those of medieval peasants and the changes brought by clocks and industrialization. It draws on works such as Schor's The Overworked American.

A Veritasium video that follows the principle of least action from Bernoulli and Newton to quantum mechanics, asking whether light takes all possible paths at once. It includes experiments showing quantum waves.

A doctor from Medlife Crisis explains in under three minutes why even a rich patient should not simply order every medical test, touching on pre-test probability and Bayesian reasoning. False positives make blanket testing counterproductive.

ElectroBOOM examines whether 5G and other electromagnetic waves can harm people, explaining the EM spectrum and the difference between ionizing and non-ionizing radiation. It includes experiments and measurements in his usual humorous style.

Veritasium presents David Sinclair's information theory of aging, which says aging is a loss of epigenetic information, and the evidence that aging can be slowed or reversed. It touches on stressors like fasting, exercise and cold exposure.

Veritasium explains that the US signed the Metre Convention in 1875 and that all US customary units are officially defined in terms of metric standards. It also touches on the standard kilogram.

CGP Grey narrates an animated adaptation of Nick Bostrom's Fable of the Dragon-Tyrant. The story uses a dragon that demands a daily toll of lives as a metaphor for aging and society's acceptance of death.

An animated visualization of basic quantum mechanics using a free particle, with simulations based on the actual equations. It covers waves, particles, and how measurement collapses the wavefunction.

3Blue1Brown builds toy SIR models to simulate how an epidemic spreads and tests scenarios like social distancing, travel restrictions, central gathering places and quarantine. It was made during the early COVID-19 outbreak.

CGP Grey explains that postal codes are routing instructions for mail rather than geographic regions. He looks at the quirks and problems this causes.

A short Healthcare Triage episode by Aaron Carroll arguing that milk gets an undeserved pass in efforts to improve diets. It examines claims about calcium and bone strength and concludes you don't need to drink milk.

A cardiologist runs a detailed, skeptical review of the Wim Hof Method, covering the research on cold exposure and breathing techniques. It also teaches how to read scientific statistics critically.

An animated Kurzgesagt explainer on bacteriophages, viruses that kill bacteria, covering how they infect and burst cells and their potential as therapy against antibiotic-resistant bacteria.

Science journalist potholer54 examines the claim that SARS-CoV-2 came from a Wuhan lab, tracing the sources behind it and the weaknesses in the evidence.

A Kurzgesagt animated explainer on whether aging could be cured within our lifetimes, made with Lifespan.io and the LEAF foundation. It introduces the idea of treating aging as a medical problem.

The Thought Emporium's update on the home-brewed gene therapy he took to cure his lactose intolerance. It reports how the effect held up over two years and what future versions might look like.