tolerance
18:33I Genetically Engineered *MYSELF* to Fix Lactose Intolerance
640K views • 8 years ago
The Thought Emporium
The Thought Emporium's host describes making and taking a DIY gene therapy to treat his own lactose intolerance. It uses an AAV virus to deliver DNA coding for the lactose-digesting enzyme, made with biohacker Gabriel Licina's help.
57:24Rhonda Patrick: Nutrigenomics, Epigenetics, and Stress Tolerance
118K views • 11 years ago
TheIHMC
Rhonda Patrick gives an IHMC talk on how genetic variation affects micronutrient absorption and metabolism, and how diet changes gene expression. It also covers epigenetics, including heritable changes, and stress tolerance.
11:32Erlang: The Movie (Fixed Audio)
43K views • 9 years ago
CH1LLW4VE
A 12-minute film in which Erlang's creators demonstrate the language's fault tolerance and live-system features, including phoning each other to show it working. This version has fixed audio.
Topic match · Distributed systems
42:03The Soul of Erlang and Elixir • Sasa Juric • GOTO 2019
384K views • 7 years ago
GOTO Conferences
Sasa Juric explains what makes Erlang and Elixir suited to server-side systems, focusing on the BEAM concurrency model rather than syntax or ecosystem. He demonstrates processes, supervision, and fault tolerance.
Topic match · Distributed systems
1:10:23"Systems that run forever self-heal and scale" by Joe Armstrong (2013)
85K views • 5 years ago
Strange Loop Conference
Joe Armstrong's Strange Loop 2013 talk on building large scalable systems from small isolated parallel components. It covers detecting and correcting errors at run time, changing code while it runs, and how Erlang embodies these principles.
Topic match · Distributed systems
56:19MINIX 3: a Modular, Self-Healing POSIX-compatible Operating System
90K views • 16 years ago
FOSDEM
Andrew Tanenbaum's FOSDEM 2010 talk on MINIX 3, a microkernel OS built for high reliability and security. It shows how the system detects and recovers from device driver crashes, and addresses microkernel performance concerns.
Topic match · Distributed systems
11:32Erlang: The Movie
175K views • 14 years ago
uncertainyesterday
A short Ericsson film demoing Erlang, showing concurrent processes, debugging tools, and hot code reloading, including crashing parts of a running system while calls continue.
Topic match · Distributed systems
35:15Solid Ground // Saša Jurić
14K views • 9 years ago
EMPEX Conference
Sasa Juric's EMPEX talk demonstrates Elixir and Erlang's process model and what makes the BEAM runtime distinctive, such as fault-tolerant parallelism by design.
Topic match · Distributed systems
9:58Erlang: The Movie
159K views • 19 years ago
dawsdesign
A short film about the Erlang language, showing telecom systems built from lightweight processes and demonstrating hot code swapping. It is an edited version of the original Ericsson video.
Topic match · Distributed systems
45:31The Do's and Don'ts of Error Handling • Joe Armstrong • GOTO 2018
74K views • 8 years ago
GOTO Conferences
Joe Armstrong, inventor of Erlang, gives a GOTO Chicago 2018 talk on building fault-tolerant systems. He covers what to do and avoid when handling errors, arguing for letting processes fail and recover.
Topic match · Distributed systems
57:39The Stellar Consensus Protocol | David Mazières | Talks at Google
56K views • 10 years ago
Talks at Google
David Mazieres presents the Stellar Consensus Protocol at Google, introducing federated Byzantine agreement. The model lets participants choose whom to trust rather than assuming fixed membership.
Topic match · Distributed systems
12:24Am I still lactose tolerant? - Lactose Gene Therapy Update
765K views • 6 years ago
The Thought Emporium
The Thought Emporium's update on the home-brewed gene therapy he took to cure his lactose intolerance. It reports how the effect held up over two years and what future versions might look like.
5:14Tom Lehrer - National Brotherhood Week - with intro
694K views • 18 years ago
The Tom Lehrer Wisdom Channel
Tom Lehrer performs his satirical song "National Brotherhood Week" with a spoken intro. The song mocks superficial displays of tolerance while prejudices between groups carry on.
40:20"Testing Distributed Systems w/ Deterministic Simulation" by Will Wilson
55K views • 12 years ago
Strange Loop Conference
Will Wilson of FoundationDB explains how the team tested their distributed database using deterministic simulation. By running the whole system in a simulator with injected faults and reproducible seeds, they could find rare concurrency and network bugs.
Topic match · Distributed systems
49:15Erlang Factory 2014 - That's 'Billion' with a 'B': Scaling to the Next Level at WhatsApp
50K views • 12 years ago
Erlang Solutions
Rick Reed of WhatsApp explains at Erlang Factory 2014 how the service scaled to billions of messages with a very small engineering team. He covers the FreeBSD and Erlang stack, Mnesia usage, server counts and bottleneck work.
Topic match · Distributed systems
47:43"Turning the database inside out with Apache Samza" by Martin Kleppmann
205K views • 12 years ago
Strange Loop Conference
Martin Kleppmann argues that databases are global shared mutable state and proposes treating them as an ever-growing log of immutable facts. Derived data such as caches, indexes and views is then built by stream processors like Apache Samza. The talk draws on Kafka and LinkedIn's experience with commit logs.
Topic match · Distributed systems
1:02:50The Language of the System - Rich Hickey
174K views • 13 years ago
ClojureTV
Rich Hickey's 2013 talk applies language-design thinking to whole systems, covering names, queues, data, failure, and the interfaces between programs. It ends with a call to action for building systems holistically.
Topic match · Distributed systems
51:27Google I/O 2012 - Go Concurrency Patterns
894K views • 14 years ago
Google for Developers
Rob Pike's Google I/O 2012 talk shows how goroutines and channels solve tricky concurrency problems with simple Go code. It features a playful goroutine demo with gophers passing messages and a search engine example.
Topic match · Distributed systems
51:36Conflict Resolution for Eventual Consistency • Martin Kleppmann • GOTO 2016
46K views • 9 years ago
GOTO Conferences
Martin Kleppmann's GOTO Berlin 2016 talk on how collaborative editors, offline apps, and multi-datacenter databases handle concurrent updates. It covers conflict resolution approaches including operational transformation and CRDTs, with a worked look at text CRDTs.
Topic match · Distributed systems
41:06"Unison: a new distributed programming language" by Paul Chiusano
45K views • 7 years ago
Strange Loop Conference
Paul Chiusano's Strange Loop 2019 talk introduces Unison, an open-source functional language for distributed, elastic systems. It covers content-addressed code identified by hashes of the syntax tree, a codebase manager, and algebraic effects called abilities.
Topic match · Distributed systems
1:06:34Paxos lecture (Raft user study)
114K views • 13 years ago
Diego Ongaro
John Ousterhout's slides-and-voiceover lecture on Paxos, made for the Raft user study comparing how students learn Raft and Paxos. It is a full introduction to the Paxos consensus algorithm.
Topic match · Distributed systems
42:34Hewitt, Meijer and Szyperski: The Actor Model (everything you wanted to know...)
131K views • 13 years ago
jasonofthel33t
A standing whiteboard conversation at Lang.NEXT 2012 among Carl Hewitt, Erik Meijer and Clemens Szyperski about the actor model. Hewitt, who originated the model, explains its foundations.
Topic match · Distributed systems
1:19:35Lecture 1: Introduction
921K views • 6 years ago
MIT 6.824: Distributed Systems
The opening lecture of MIT 6.824 Distributed Systems (Spring 2020), introducing the course and core challenges of distributed systems. It begins a playlist that goes on to cover Raft and other consensus papers in Go.
Topic match · Distributed systems
58:36Advanced Topics in Programming Languages: A Lock-Free Hash Table
29K views • 14 years ago
GoogleTalksArchive
A 2007 Google Tech Talk in which Cliff Click of Azul Systems presents a lock-free concurrent hash table that scales to 768 CPUs. He explains why it is correct by reasoning in a different way than usual happens-before and memory-order arguments.
Topic match · Distributed systems
52:29"I See What You Mean" by Peter Alvaro
59K views • 11 years ago
Strange Loop Conference
Peter Alvaro's Strange Loop 2015 talk argues that query languages let you state what you mean, and applies that to distributed programming. It covers Datalog, Dedalus and the Bloom lineage for reasoning about distributed systems.
Topic match · Distributed systems
14:36Distributed Systems 1.1: Introduction
382K views • 6 years ago
Martin Kleppmann
The first lecture in Martin Kleppmann's 8-lecture distributed systems series from the University of Cambridge undergraduate course. It introduces the subject, and accompanying lecture notes are available.
Topic match · Distributed systems
38:53ElixirConf 2018 - Docker and OTP Friends or Foes - Daniel Azuma
16K views • 8 years ago
ElixirConf
Daniel Azuma's ElixirConf 2018 talk on whether Docker and OTP conflict. He shows they can coexist and uses Horde and DeltaCrdt, with a live tank-game demo, to keep state alive across container kills.
Topic match · Distributed systems
1:01:46GigCityElixir23 - Bryan Hunter
10K views • 3 years ago
Groxio
Bryan Hunter's GigCityElixir 2023 talk on HCA Healthcare's Waterpark system, built on Elixir/Erlang. It describes how the architecture is distributed and fault-tolerant, with a multi-datacenter cluster and runtime code swapping.
Topic match · Distributed systems
59:50Leslie Lamport: Thinking Above the Code
403K views • 12 years ago
Microsoft Research
Leslie Lamport argues that programmers, like architects, should write rigorous specifications before coding, especially for concurrent and distributed systems. The talk introduces the case for writing specs (the TLA+ mindset) as a way of thinking above the code.
Topic match · Distributed systems
40:13Zach Tellman - Everything Will Flow
27K views • 11 years ago
ClojureTV
Zach Tellman's Clojure West talk covers the basics of queueing theory and its practical use in systems, including backpressure, how queues break down under load, and pitfalls of naive core.async use.
Topic match · Distributed systems
1:33:27AWS re:Invent 2016: Tuesday Night Live with James Hamilton
133K views • 9 years ago
Amazon Web Services
James Hamilton's Tuesday Night Live keynote at AWS re:Invent 2016, touring AWS infrastructure at scale including networking, power and custom silicon. It also features NASA JPL's Tom Soderstrom.
Topic match · Distributed systems
54:54Breakout Session Presented by Dan Robinson of Heap at PGConf Silicon Valley 2015
14K views • 10 years ago
Citus Data
Dan Robinson, then CTO of Heap, explains how Heap runs its product analytics backend on PostgreSQL and CitusDB. It covers conversion funnels, retention and cohort queries across tens of billions of events and 50 TB of data, plus Postgres and Kafka together and the indexing strategy.
Topic match · Distributed systems
1:08:17How We've Scaled Dropbox
372K views • 14 years ago
Stanford
Dropbox engineer Kevin Modzelewski gives a Stanford colloquium on Dropbox's history and the technical problems it faced scaling, including detailed database schema decisions.
Topic match · Distributed systems
59:47Classic Game Postmortem: Ultima Online
184K views • 8 years ago
GDC Festival of Gaming
A 2018 GDC panel where Raph Koster, Starr Long, Richard Garriott and Rich Vogel look back on what went right and wrong building and running Ultima Online. They share candid stories from the early days, including player behavior and server architecture.
Topic match · Distributed systems
1:49:07I Shot You First: Networking the Gameplay of Halo: Reach
58K views • 8 years ago
GDC Festival of Gaming
Bungie's David Aldridge explains the networking programming behind Halo: Reach in a 2011 GDC session. It covers how gameplay stays in sync online, including forecasting and state reconciliation.
Topic match · Distributed systems
32:02Autonomous Testing and the Future of Software Development - Will Wilson
7K views • 7 years ago
The Linux Foundation
Will Wilson explains autonomous testing: using deterministic simulation and fuzzing, building on FoundationDB's approach, to test software continuously. It sets out the ideas behind his later company Antithesis.
Topic match · Distributed systems
28:21Velocity 2012: Richard Cook, "How Complex Systems Fail"
60K views • 14 years ago
O'Reilly
Dr. Richard Cook, a physician and patient safety researcher, presents his ideas on how complex systems fail, at Velocity 2012. He argues for designing for resiliency rather than trying to exhaustively handle every failure mode.
Topic match · Distributed systems
20:45dotJS 2019 - James Long - CRDTs for Mortals
18K views • 6 years ago
dotconferences
James Long's dotJS 2019 talk on how CRDTs enable local-first apps and how simple they can be to implement. He shows how to use them to build robust offline-capable frontends.
Topic match · Distributed systems
34:52Liberating Distributed Consensus - Heidi Howard
7K views • 7 years ago
Reactive Summit
Heidi Howard's Reactive Summit 2018 talk on generalizing Paxos by weakening its original requirements. She shows Paxos is one point on a broad spectrum of consensus approaches.
Topic match · Distributed systems
58:17Raft lecture (Raft user study)
87K views • 13 years ago
Diego Ongaro
John Ousterhout lectures on the Raft consensus algorithm, made for the Raft user study comparing how students learn Raft and Paxos. It covers leader election and log repair.
Topic match · Distributed systems