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A short clip of molecular biologist Cristina Sanchez describing her lab research on how THC affects cancer cells. It is uploaded on a channel promoting cannabis as a cancer treatment.

Persi Diaconis explains on Numberphile the mathematics of card shuffling, including why seven riffle shuffles are needed to randomize a deck and how different shuffles compare.

Yannic Kilcher interviews Emad Mostaque, founder of Stability AI, about the company's funding, its mission, and the release of Stable Diffusion. Topics include access to compute, handling harmful outputs, and avoiding the corrupting influence of profit.

A short clip of George R.R. Martin asking Stephen King on stage how he writes so fast. King describes setting daily page goals, around six pages a day, and keeping focused hours.

A long Lex Fridman interview with Stephen Wolfram on complexity, cellular automata, computational irreducibility and the Wolfram Physics Project.

Pixar staff tell the story of how Toy Story 2 was almost deleted from the studio's computers and was saved by a home computer backup.

John Conway talks in a short Numberphile interview about his mixed feelings toward the Game of Life, his most famous invention. He says he is not especially pleased that it overshadowed his other work.

Fox Business interview in which Oracle co-founder Larry Ellison claims Oracle will beat Amazon at cloud databases. He argues the world's valuable data lives in Oracle and says Amazon struggled to move off it.

Joe Armstrong, creator of Erlang, interviews Alan Kay at Code Mesh. They discuss the meaning of object orientation, message passing, the META II paper, and the state of computer science.

A short excerpt from a 1994 interview of Steve Jobs in which he says everything around us was made up by people no smarter than you, and that you can change and shape the world.

A standing whiteboard conversation at Lang.NEXT 2012 among Carl Hewitt, Erik Meijer and Clemens Szyperski about the actor model. Hewitt, who originated the model, explains its foundations.

A 1968 Firing Line interview in which Milton Friedman explains the negative income tax, a proposal to replace welfare bureaucracy with direct payments.

An excerpt of Simon Sinek on Inside Quest discussing millennials in the workplace. He covers parenting, technology, social media dopamine and what that means for managers.

A three-minute clip of Jeff Bezos describing his Regret Minimization Framework: imagining yourself at 80 to decide whether to leave a Wall Street job to start Amazon.

An excerpt from the 1983 BBC series Fun to Imagine in which Richard Feynman describes how he and a mathematician friend counted in their heads in different ways, one verbally and one visually. It shows that people can reach the same goal through quite different mental methods.

A short excerpt of Jon Stewart interviewing former Treasury Secretary Larry Summers about the causes of inflation and whether workers or corporate profits are to blame. It comes from an episode of The Problem With Jon Stewart.

A two-minute clip from a 1994 interview with Steve Jobs by the Santa Clara Valley Historical Association. Jobs talks about failure and about how most people never ask for help, recalling that he simply called people to ask.

A Channel 9 Going Deep interview in which Brian Beckman talks with Rich Hickey, creator of Clojure, about the language's design. It covers Clojure's persistent data structures, reference types and its approach to concurrency on the JVM.

Charlie Rose interviews Sir James Goldsmith in 1994 about the coming GATT free-trade agreement. Goldsmith predicts that global capital mobility will upset the balance between capital and labor.

A two-minute video of Ira Glass on the creative process, describing the gap between taste and skill when starting out and urging you to keep producing until your work matches your taste.

Fraser Cain interviews JPL physicist Slava Turyshev about using the Sun's gravity as a lens to image distant exoplanets. They cover how the lens works, how a spacecraft would align with it, and mission design.

A two-hour extended interview in which Crash Bandicoot co-creator Andy Gavin tells how he and Jason Rubin built the game at Naughty Dog. It includes the custom Lisp tools used.

Lex Fridman interviews Harvard astrophysicist Avi Loeb about the interstellar object Oumuamua, aliens and black holes. Loeb lays out his argument that it may be an artifact rather than debris.

A 1984 Computer Chronicles segment in which Susan Kare explains the ergonomics and interface design of the original Macintosh. She introduces the interface step by step for newcomers.

Physicist Roger Penrose and philosopher William Lane Craig discuss the origin of the universe on the Unbelievable? show. Topics include Penrose's three realms of reality, conformal cyclic cosmology and whether fine tuning points to a creator.

Sixty Symbols interviews Nottingham cosmologist Tony Padilla, who says string theory deserves to be taken seriously. He explains how strings emerged from the equations rather than being invented.

A short clip of Simon Peyton Jones talking about the future of programming languages, saying Haskell is useless in the sense that pure programs cannot have effects, while mainstream languages are useful but unsafe. He describes languages converging, with ideas such as STM and LINQ moving between them.

Brian Kernighan explains how grep came to be, written overnight by Ken Thompson, and how it got its name from the ed command g/re/p. He also covers the lineage from QED to ed that led to it.

A student interviews Kirsten Carlson, who does not have an internal monologue, and she answers questions about how she thinks. The video grew out of a viral article about people lacking inner speech.

WSJ's Joanna Stern interviews Apple's Craig Federighi and Greg Joswiak at WWDC 2025 about Siri's delays, AI strategy, the Liquid Glass redesign in iOS 26, iPad versus Mac, and tariffs.

A five-minute clip from Donald Knuth's Web of Stories interviews in which he gives advice to young people, including being wary when too many people adopt an idea.

Jim Coplien and Bob Martin debate test-driven development and unit testing in an InfoQ video that grew out of a JAOO 2007 dispute. They also touch on design and architecture.

A short excerpt of Elon Musk, interviewed by Kevin Rose, explaining first-principles reasoning with the example of the car versus improving horse carriages. He warns it takes much more mental energy than reasoning by analogy.

A roughly 14-minute interview with OpenBSD founder Theo de Raadt at ruBSD 2013. He talks about making painful changes, getting real feedback, mitigation techniques compared to other OSs, and virtualization.

Chamath Palihapitiya's Stanford GSB View From The Top talk on money as an instrument of change. HN mostly knows it for his remarks on social media's dopamine-driven feedback loops and regrets about Facebook.

A travel vlogger asks the leader of the Hadza hunter-gatherers in Tanzania some big life questions just before a baboon hunt. The short answers touch on meat, honey and what matters in life.

Brady Haran interviews Brother Guy Consolmagno, director of the Vatican Observatory, for Sixty Symbols. It is part of a three-video set along with the observatory's telescopes and its meteorite collection.

Dwarkesh Patel interviews Andy Matuschak on how he learns, why memorization matters for understanding, and why most learning tools fail. The conversation also covers handling confusion and the role of tutoring.

GitHub interviews Linus Torvalds on twenty years of Git, from its creation in about ten days as a Linux kernel tool to its role in modern software development. He discusses technical decisions, community contributions and the project's philosophy.

A five-minute clip in which Erich Fromm asks whether the purpose of work is just making money. He argues that white-collar workers end up selling their personality, relating to others the way goods relate to each other on a market, and he points to creative pleasure, participation and usefulness to society as what work could offer instead.