practical effects

A short clip of Simon Peyton Jones talking about the future of programming languages, saying Haskell is useless in the sense that pure programs cannot have effects, while mainstream languages are useful but unsafe. He describes languages converging, with ideas such as STM and LINQ moving between them.

Rhonda Patrick interviews Salk Institute researcher Satchidananda Panda about circadian rhythms and the timing of food. They cover time-restricted feeding and its links to obesity, muscle mass, heart health, and light exposure.

A long interview by Blender Guru with Ton Roosendaal, creator of Blender. They cover Blender's origins, the move to open source, why Ton is not driven by money, Autodesk, and what sets Blender apart from other open source projects.

Pixar staff tell the story of how Toy Story 2 was almost deleted from the studio's computers and was saved by a home computer backup.

Asian Boss interviews Professor Kim Woo-joo of Korea University Guro Hospital about COVID-19 in early 2020. He covers masks, testing, aerosol spread, and South Korea's response.

Rhonda Patrick interviews USC gerontologist Valter Longo about fasting, the fasting-mimicking diet, and their effects on longevity, cancer, and multiple sclerosis. They discuss mechanisms such as IGF-1 and autophagy and clinical trials.

YC partner Michael Seibel discusses his essay on real product-market fit, why founders wrongly believe they have it, and how building a company is not a single-variable problem, drawing on Justin.tv and Socialcam.