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David Shaw of D. E. Shaw Research presents Anton, a special-purpose machine that speeds up biomolecular simulations about a hundred-fold. The lecture covers molecular dynamics and how simulation helps understand how drugs bind.

Eric Weinstein's roughly three-hour presentation of Geometric Unity, his proposed theory unifying physics, given as a special episode of The Portal. It includes clarifications at the end.

A special lecture from MIT's Private Pilot Ground School in which Lt. Col. Randy Gordon, a fighter and test pilot, describes F-22 flight controls. Topics include thrust vectoring, the pilot command system and how software handles failures.

Hennessy and Patterson's 2018 Turing Award lecture at ISCA, A New Golden Age for Computer Architecture. It covers domain-specific hardware, security, open instruction sets and agile chip development.

Brian Kernighan gives a talk at the University of Nottingham on how to succeed in language design without really trying. He draws on his experience with awk and other languages.

Bill Dally of NVIDIA gives a University of Washington lecture on trends in deep learning hardware. It covers numeric formats, specialized instructions, energy per operation and co-design of hardware and software.

A long Mill Computing lecture on the Mill CPU's compiler toolchain, covering the specializer that targets family members, scheduling and latency passes, and the belt. It explains how the compiler handles a wide-issue, exposed-pipeline design.

James D'Angelo argues that the 1970 Legislative Reorganization Act made congressional votes public, opening the door to lobbyists and special interests. He proposes restoring secret voting as a cheap fix for corruption and many social ills.

Dr. Roger Seheult of MedCram reviews the benefits of sunlight beyond vitamin D, covering the solar spectrum, circadian rhythm, melatonin and infrared light. The lecture runs nearly two hours with timestamps.

Lawrence Krauss's 2009 talk on the current picture of the universe, how it will end and how it could have come from nothing. It covers the expanding universe, cosmic background radiation and the cosmological constant.

Russian-American journalist Vladimir Pozner lectures at Yale on how US foreign policy toward Russia after the Soviet collapse shaped Putin, then takes audience questions on election interference, the Skripal poisoning and media independence.

Sean Carroll introduces his video series on the biggest ideas in physics, such as symmetry, space and matter, as informal discussions with follow-up Q&A videos. This is the short opening video of the series.

Floyd Toole's CIRMMT distinguished lecture on the science of sound reproduction, drawing on decades of blind listening research. It covers what listeners prefer in loudspeakers and why measured accuracy and anechoic response matter.

Neil Postman's 1997 lecture at College of DuPage, based on his book, argues that Americans treat technology as a national religion and depend on it to solve larger human problems. It includes audience questions.

Sebastien Bubeck presents the Sparks of AGI paper at MIT, showing early experiments with GPT-4 across many domains and asking whether artificial intelligence has arrived. It includes the TikZ unicorn example.

University of Chicago lecture in which John Mearsheimer argues the West, through NATO and EU expansion, bears primary responsibility for the Ukraine crisis. He also discusses how to end it and its consequences.

The opening lecture of the How to Start a Startup course at Stanford, with Sam Altman covering ideas and products and Dustin Moskovitz discussing why to start a startup.

Lord David Willetts argues at the Royal Institution that the post-war baby boomers gained wealth and security at the expense of younger generations. He draws on his book The Pinch, covering housing, wealth and social policy in the UK.

Y Combinator partner Pete Koomen, who led Optimizely to $100M ARR, walks through the enterprise sales funnel. Chapters cover prospecting, outreach, qualification, pricing, closing, procurement and implementation.

Part 10 of Dan Gelbart's prototype-building lecture series, covering flexures: flexible joints that give precise, frictionless motion. It shows how a cheap piece of aluminum can become a nanometer-accurate mechanism.

A 3Blue1Brown live lockdown math episode asking what Euler's formula e^(pi i) is actually saying. It builds intuition through exponentials, rotation and vectors landing on the unit circle.

An excerpt from Russell Barkley's lecture on ADHD, focusing on inhibition, impulsivity and emotional regulation. It explains ADHD as a problem of response inhibition and emotional impulsivity.

The second talk in the Mill CPU series by Mill Computing, covering the Belt, the Mill's operand-passing model that replaces general registers. It explains the cost of register renaming in conventional wide CPUs and how the Belt reaches high instruction-level parallelism.

Simon Peyton Jones's first lecture on types in Haskell from the Oregon Programming Languages Summer School 2013. It covers type classes and how they relate to OOP, subtyping and polymorphism.