dna replication

Destin of Smarter Every Day goes behind the scenes at the 23andMe lab to show how genotyping works. He also discusses DNA testing and privacy.

A compilation of molecular animations of DNA replication and gene transcription by Drew Berry and Etsuko Uno at WEHI, made with no narration. It shows molecular machinery at work inside cells.

Drew Berry shows scientifically accurate animations of molecular processes inside cells, such as DNA replication, at TEDxSydney.

Dwarkesh Patel interviews ancient-DNA geneticist David Reich about human prehistory, including the small group that left Africa around 70,000 years ago and the Yamnaya expansion.

Veritasium explains how investigators caught the Golden State Killer using forensic genealogy, matching crime scene DNA to distant relatives in public genealogy databases. It also covers the privacy implications of DNA databases.

Veritasium explains why a large share of published research findings may be false, covering p-values, p-hacking, publication bias and low replication rates. It draws on John Ioannidis's well-known paper and describes reforms such as preregistration.

John Sotos, a physician and former Intel chief medical officer, argues at DEF CON 25 that genetic diseases are exploitable vulnerabilities in the genome. He warns that CRISPR and related tools will make malicious genome hacks and targeted bioweapons feasible.

A two-minute clip of Richard Feynman explaining why he considers much of social science pseudoscience. He stresses how easy it is to fool yourself and how much care real knowledge takes.

A three-hour PyCon 2016 tutorial by Christophe Pettus that orients Python developers to PostgreSQL. It covers installation, administration, and use, including vacuuming, MVCC, replication and backups.

Geoff Cumming uses a simulation to show how wildly the p value varies from one replication to the next because of sampling variability. He argues for estimation and confidence intervals over null hypothesis significance testing.

Illumina's 3D animation of its sequencing-by-synthesis workflow, from sample preparation and cluster generation to sequencing on a flow cell and data analysis.

A short animation from the DNA Learning Center showing how mRNA carries a gene's message to the ribosome, where tRNA and codons are used to assemble amino acids into a protein.

John Oliver's Last Week Tonight segment on how media outlets report incomplete or untrue findings as settled science. It covers sensational headlines, small studies and pressure on researchers.

Martin Kleppmann surveys current research on CRDTs, the algorithms for merging concurrent edits across offline replicas. He covers the hard parts such as rich text, moves and merge results that are technically correct but poor.

Veritasium tells the story of Kary Mullis, the surfer and LSD user who invented PCR and won a Nobel Prize. It explains how PCR works and how it was developed at Cetus.

Researchers from the Artificial Life Lab Graz introduce the Primordial Particle System, where a simple motion law for self-propelled particles produces cell-like structures that self-reproduce and show life cycles.

Dr Brad Stanfield recounts the research history and scandal around resveratrol, the supposed anti-aging supplement, including problems with the original studies.

A 72-minute Q&A with Linus Torvalds at DebConf 14. Topics include the pain of distributing Linux binaries, distro fragmentation, kernel backwards compatibility, GPLv2 versus GPLv3 and conduct.

A very short clip of Bill Gates hitting a Blue Screen of Death while demonstrating plug and play on Windows 98 on stage.

The Thought Emporium's host describes making and taking a DIY gene therapy to treat his own lactose intolerance. It uses an AAV virus to deliver DNA coding for the lactose-digesting enzyme, made with biohacker Gabriel Licina's help.

Cal Henderson's DjangoCon 2008 keynote, "Why I Hate Django", is a funny critique of Django from a Flickr architect. It touches on scaling topics such as database replication.

A Capella Science parody of Despacito that sings through evolutionary developmental biology, explaining how a single cell becomes a body, including body-axis genes and dormant snake leg DNA. It runs about four minutes.

An Onion News Network sketch in which two teenage girls appear on TV to plead for their kidnapped friend's release, then start gossiping about classmates. It is a satirical parody of teen behavior and sensational news.

Journalist Matthew Cole's Black Hat 2013 talk on the CIA's operational security failures in the 2003 Milan kidnapping. Phone and location metadata exposed the team and led to arrest warrants.

Matt Parker's LMS popular lecture on how seemingly incredible results can be meaningless random patterns. He ranges from ancient Woolworths civilisations to shoelaces and DNA.

The Thought Emporium shows how easily bacteria can be genetically modified to produce fluorescent proteins and even bioluminesce, with techniques doable at home. It links to companion videos on incubators, DNA extraction and gels.

Jim Keller, CTO of Tenstorrent, gives a keynote at Stanford's System X conference on change, understanding and the future of computing. He touches on Moore's Law, how far transistors are from physical limits, and ideas like DNA origami.

A two-minute clip of Richard Feynman on the social sciences, discussing what counts as real science versus pseudo science.