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Eugenia Cheng gives the opening keynote at Lambda World 2017, presenting category theory as very abstract algebra whose abstraction gives it broad applicability. She applies it to everyday questions including privilege and prejudice.

Sebastian Seung's TED talk introduces the connectome, the map of neural connections he argues defines each person. He explains how mapping it could change how we understand brains and minds.

Neurologist Dr. Matthew Phillips talks at Low Carb Gold Coast 2022 about fasting and ketogenic diets as therapies for cancer and neurodegenerative disease. He focuses on mitochondrial dysfunction and brain energy metabolism.

George Friedman of Stratfor speaks at the Chicago Council on Global Affairs about flashpoints in Europe that he expects to erupt again, including borderlands and cultural fault lines.

Ted Nelson's short eulogy for Douglas Engelbart, delivered at the Computer History Museum in 2013, reflecting on his friend and Engelbart's ideas.

Geoffrey Hinton's Google Tech Talk linking machine learning to biology, explaining dropout as a form of model averaging and why sexual reproduction and stochastic spiking neurons may prevent overfitting.

UCLA professor Dario Nardi presents brain-imaging research suggesting that different Myers-Briggs personality types use their brains in different ways. He discusses how each type can reach a state of creative flow. It is aimed at a general audience.

Physicist David Deutsch's TED talk on why science took off, arguing that good explanations are those that are hard to vary. It contrasts scientific explanation with myth.

An excerpt from an RSA event in which physicist David Deutsch makes the case for optimism as a driver of progress in the 21st century. It is a short highlight of a longer discussion.

Michael Levin's NeurIPS 2018 talk on bioelectric computation outside the nervous system, showing how cell electrical networks shape development and regeneration. It covers morphological information processing in living tissue.

Dr. Jason Fung, a nephrologist, explains therapeutic fasting as a treatment for obesity and type 2 diabetes. He frames it around the two-compartment problem of fat storage and insulin resistance.

Zach Tellman's Clojure West talk covers the basics of queueing theory and its practical use in systems, including backpressure, how queues break down under load, and pitfalls of naive core.async use.

A 2015 talk by David Deutsch with slides and audio about constructor theory and how physics, in particular the many-worlds interpretation, can be framed without probability.

A Ropecon 2019 talk by a lighting designer and a software engineer on how the Odysseus larp spaceship was built, using over ten IT systems, hundreds of lights and dozens of speakers. It covers the lessons learned.

Stuart Armstrong of the Future of Humanity Institute gives an Oxford physics talk on what exploratory engineering suggests about the Fermi paradox. He argues that von Neumann probes and Dyson spheres are plausibly buildable and asks what traces advanced civilizations would leave.

David Deutsch's TED talk arguing that humanity's survival depends on solving problems through knowledge growth. He frames people as improbable "chemical scum" capable of understanding distant quasars.

Andrej Karpathy, then Tesla's head of AI, presents at ScaledML 2020 on how Tesla builds full self-driving using vision-based neural nets and fleet data collection. He covers training custom detectors and neural nets gradually replacing traditional code.

Dr. Howard Schubiner presents his research that much chronic pain comes from learned neural pathways rather than structural damage, and outlines a treatment approach based on that view.

Robert Erdmann, a materials scientist at the Rijksmuseum, gives a PyCon keynote on the ultra-high-resolution imaging of Rembrandt's Night Watch. He covers the automated gantry camera system, the Python software that drives it, and the large volumes of image data involved.

Max Tegmark's MIT CBMM talk on why deep learning works so well. He argues that the laws of physics and the symmetries in physical data make it compressible into small neural networks, tying physics to network structure.

Andrej Karpathy, then Tesla's head of AI, gives a CVPR 2021 workshop keynote on how Autopilot's neural networks work. A large part covers the move to a vision-only stack, including why radar was dropped and how vision produces depth estimates.

David Rock gives a Google Tech Talk based on his book Your Brain at Work, using neuroscience to explain why focus and productivity are hard at the office. He gives strategies for managing mental energy and distraction.

Neuroscientist Anil Seth argues in this TED talk that perception is a controlled hallucination: the brain constantly predicts the world and our shared agreement is what we call reality. He also touches on the construction of the self.

Neuroscientist Beau Lotto runs the audience through color and pattern illusions to show that perception is shaped by context and evolutionary history rather than being a direct readout of the world. The talk is playful and hands-on, and it argues that the brain interprets ambiguous signals.

Andrej Karpathy's Databricks talk on Software 2.0, the shift from human-written code to code produced by neural network training. It covers how developer work moves toward curating datasets, the advantages and challenges, and opportunities for new tooling.

Berkeley neuroscientist Jack Gallant shows how fMRI brain mapping can be used to decode what a person sees, with visualizations of brain activity and its implications.

Dan Abramov live-codes hot reloading with time-travel debugging at React Europe 2015, debuting Redux and its devtools. The slides themselves are driven by application state.

Cheng Lou's react-europe 2016 talk lays out a mental framework for thinking about abstraction levels in JavaScript tooling, from Angular and Grunt to Webpack and React. It uses that framework to reason about the cost of abstractions and how to choose between competing solutions.

Netflix engineer Drew Gallatin's EuroBSDcon 2022 talk quantifies the older FreeBSD optimizations that let Netflix serve web traffic at 800Gb/s, including TSO, LRO, VM page cache zones, asynchronous sendfile and unmapped mbufs.

Richard Feldman's Elm Europe 2017 talk on how to structure and scale large Elm applications, including when to nest messages.

Allan Jude of Klara presents work on making ZFS scale on fast NVMe storage, covering fixes to the TaskQueue interface and removal of bottlenecks. The talk was given at EuroBSDcon 2022 and describes raising write throughput from about 3 to over 7 GB/sec.

Yanis Varoufakis talks at a festival in Zagreb about his book The Global Minotaur. He argues the postwar global economy and the 2008 crisis stem from deeper structural causes than greed or weak regulation.

Marshall Kirk McKusick gives a talk at EuroBSDCon tracing filesystem and storage development from 1979 to today, using the BSD Fast Filesystem as the focus. It covers early disk-geometry optimization through later contiguous layout and small-file performance work.

Gary Wilson's TEDxGlasgow talk argues that internet pornography hyperstimulates the brain's reward system and can cause symptoms that reverse when people stop. TED notes that several claims are not supported by respected academic studies.

David Heinemeier Hansson's talk at Startup School 2008 on building a profitable startup. He argues for bootstrapping and small, well-run companies instead of chasing investment and exits.

Andrew Ng presents unsupervised feature learning and deep learning, showing how algorithms can learn representations from unlabeled data instead of hand-designed features. He gives examples in vision and audio, including visualizations of features learned by successive layers.

Travis Kalanick's talk at FailCon 2011 about his earlier failed startups, given as a case study before Uber's rise. It describes lessons from those ventures.

Gary Vaynerchuk's keynote at RailsConf 2010 in Baltimore. The Wine Library TV founder talks about building a business and audience through genuine effort and caring about customers.

Psychology professor Lisa Feldman Barrett presents her research on what emotions are, arguing that the brain constructs them rather than reading them off faces. She says this means we have more control over our emotions than we think.

A 1992 MIT Sloan talk and Q&A by Steve Jobs, then CEO of NeXT, covering NeXT's strategy, co-creating Apple, his ouster, and the value of direct experience. It ranges across technology, business and career advice.