insulin

Cardiologist Dr. Pradip Jamnadas lectures on the rationale for dietary restriction and fasting, covering insulin resistance, glucose intolerance, and low-carb eating over about 81 minutes.

Dr. Jason Fung, a nephrologist, presents his view of the causes of obesity and type 2 diabetes, focusing on hormones such as insulin rather than calories alone. The talk draws on research and his Intensive Dietary Management program.

Dr. Jason Fung lectures on why obesity became an epidemic since the 1970s, arguing insulin and hormones rather than calories drive weight gain. He explains why calorie counting fails and touches on low-carb eating and fasting.

Robert Lustig of UCSF lectures on the biochemistry of sugar, arguing that fructose and lack of fiber drive the obesity epidemic via insulin. It is the widely viewed 90-minute talk that popularized the anti-sugar case.

Dr. Jason Fung, a nephrologist, explains therapeutic fasting as a treatment for obesity and type 2 diabetes. He frames it around the two-compartment problem of fat storage and insulin resistance.

Dr. Sarah Hallberg argues in a TEDx talk that type 2 diabetes can be treated and potentially reversed through diet, especially by restricting carbohydrates. TED flagged the talk as outside its guidelines and warned against taking it as medical advice.

Gary Taubes presents the argument of his book Why We Get Fat to Googlers in 2011. He claims the type of calories matters more than the count, challenges calories-in-calories-out thinking and criticizes the low-fat dietary consensus.

A long Huberman Lab podcast episode with Dr. Robert Lustig on the calories-in, calories-out model and how sugar, fructose, fiber and processed foods affect insulin, liver and metabolic health.